| Autor: |
Modupeola A. Oguntoye, Olufunke O. Ezekiel |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Food Chemistry Advances, Vol 4, Iss , Pp 100641- (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2772-753X |
| DOI: |
10.1016/j.focha.2024.100641 |
| Popis: |
Expanding the non-dairy food and beverage matrices useful as carriers for probiotics such as Lacticaseibacillus rhamnosus GG is an ongoing concern. This has led to the development of provitamin A cassava (PAC) hydrolysate. However, the safety of novel food matrices such as PAC hydrolysate, a non-dairy probiotic beverage, needs to be assessed. The acute and 30-day sub-chronic toxicological effects of the oral administration (using oral gavage) of PAC hydrolysate without or with free or encapsulated L. rhamnosus GG, were evaluated in the Wistar rat model.No treatment-related acute toxicity, and no changes of toxicological significance (p > 0.05) in the relative organ weights, haematological or biochemical parameters were observed in all the PAC-administered Wistar rats, compared to the control. Therefore, oral administration of provitamin A cassava hydrolysate without or with free or encapsulated L. rhamnosus GG showed evidence of safety when consumed at the doses recommended in this study and not more than 30 days. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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