Isolation and biological evaluation of some organogermanium(IV) complexes of sulfonamide imine

Autor: Singh Nirmala, Kapoor Puja, Fahmi Nighat, Singh Ranvir
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Main Group Metal Chemistry, Vol 34, Iss 1-2, Pp 33-38 (2011)
Druh dokumentu: article
ISSN: 0792-1241
2191-0219
DOI: 10.1515/mgmc.2011.004
Popis: Microwave-assisted synthesis and spectroscopic studies of trimethyl and triphenyl germanium(IV) chelates derived from the reactions of organogermanium chlorides with the sodium salt of a biologically active nitrogen donor ligand are described. The resulting products have been isolated and characterized by elemental analyses, molecular weight determinations and conductance measurements, Systronics-Vadodara, India. On the basis of electronic, infrared, 1H and 13C NMR spectral studies, trigonal bipyramidal geometry has been suggested for the resulting complexes. The biologically active ligand and its corresponding complexes have been examined with regard to antifungal and antibacterial activity against pathogenic fungi and bacteria, and the results are rather encouraging. Both the compounds have also been found to act as nematicides by reducing the number of nematodes (Meloidogyne incognita).
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