| Autor: |
Akio Tada, Kozo Kuribayashi, Kazuhiro Kitajima, Akifumi Nakamura, Michiko Yuki, Shingo Kanemura, Eisuke Shibata, Yoshiki Negi, Hirotoshi Ishigaki, Yasuhiro Nakajima, Ryo Takahashi, Takashi Yokoi, Toshiyuki Minami, Takashi Kijima |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Current Problems in Cancer: Case Reports, Vol 11, Iss , Pp 100244- (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2666-6219 |
| DOI: |
10.1016/j.cpccr.2023.100244 |
| Popis: |
Paraneoplastic neurological syndrome (PNS) is rarely associated with malignant pleural mesothelioma (MPM). We report the first case of sarcomatoid mesothelioma in a 63-year-old female diagnosed with cerebellar degeneration in January 2018. Systemic examination showed right pleura thickening. The pleural biopsy of the mass revealed a sarcomatoid MPM cT3N0M0. In February 2018, anti-Ma2 antibody positivity indicated PNS complicated with MPM. First, cisplatin (75 mg/m2) + pemetrexed (500 mg/m2) chemotherapy was given. For PNS, steroid pulse therapy and high-dose immunoglobulin therapy were administered. MPM may cause anti-Ma2 antibody-related PNS. Early diagnosis and starting anticancer treatment and immunotherapy are critical. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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