Association between regional cerebral oxygen saturation and outcome of patients with out-of-hospital cardiac arrest: An observational study

Autor: Takeshi Kawaguchi, Jumpei Tsukuda, Rika Onoe, Kenichiro Morisawa, Toru Yoshida, Koichi Hayashi, Shigeki Fujitani
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Resuscitation Plus, Vol 13, Iss , Pp 100343- (2023)
Druh dokumentu: article
ISSN: 2666-5204
DOI: 10.1016/j.resplu.2022.100343
Popis: Aim: This study aimed to evaluate the association between cerebral oxygen saturation (StO2) and return of spontaneous circulation (ROSC) in patients with out-of-hospital cardiac arrest (OHCA). Methods: We retrospectively evaluated the data of patients with OHCA to determine the association between ROSC and various StO2 parameters (initial_StO2, final_StO2, mean_StO2, and Δ_StO2 [=final_StO2-initial_StO2]). Time-domain near-infrared spectroscopy was used to determine absolute StO2 values. Results: Of the 108 patients with OHCA, 23 achieved ROSC. Although initial_StO2 values did not differ between the groups, final_StO2, mean_StO2, and Δ_StO2 were higher in the ROSC group than in the non-ROSC group. The cut-off values for initial_StO2, mean_StO2, and Δ_StO2 as predictors of ROSC were 35%, 30%, and 5%, respectively. The odds ratio for ROSC had markedly increased in the Δ_StO2 ≥ 5% subgroup (19.70 [6.06–64.11], p
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