| Autor: |
Pamela Houeiss, Rachel Njeim, Hani Tamim, Ahmed F. Hamdy, Tanya S. Azar, William S. Azar, Mohamed Noureldein, Youssef H. Zeidan, Awad Rashid, Sami T. Azar, Assaad A. Eid |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Journal of Advanced Research, Vol 44, Iss , Pp 109-117 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2090-1232 |
| DOI: |
10.1016/j.jare.2022.04.013 |
| Popis: |
Introduction: The identification and validation of a non-invasive prognostic marker for early detection of diabetic kidney disease (DKD) can lead to substantial improvement in therapeutic decision-making. Objectives: The main objective of this study is to assess the potential role of the arachidonic acid (AA) metabolite 20-hydroxyeicosatetraenoic (20-HETE) in predicting the incidence and progression of DKD. Methods: Healthy patients and patients with diabetes were recruited from the Hamad General Hospital in Qatar, and urinary 20-HETE levels were measured. Data analysis was done using the Statistical Package for Social Sciences (SPSS). Results: Our results show that urinary 20-HETE-to-creatinine (20-HETE/Cr) ratios were significantly elevated in patients with DKD when compared to patients with diabetes who did not exhibit clinical signs of kidney injury (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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