RESULTS OF THE 4­YEAR PROSPECTIVE OBSERVATION IN THE PROSPECTIVE TRIAL INTEREPID: FACTORS INFLUENCING MORBIDITY AND MORTALITY IN THE POPULATION OF RURAL REGIONS OF RUSSIA AND KYRGYZ REPUBLIC

Autor: A. V. Kontsevaya, A. О. Myrzamatova, A. N. Khalmatov, M. B. Khydyakov, A. G. Polupanov, A. Т. Altymysheva, Yu. А. Balanova, А. К. Kashirin
Jazyk: ruština
Rok vydání: 2018
Předmět:
Zdroj: Кардиоваскулярная терапия и профилактика, Vol 17, Iss 2, Pp 49-56 (2018)
Druh dokumentu: article
ISSN: 1728-8800
2619-0125
DOI: 10.15829/1728-8800-2018-2-49-56
Popis: Recent decades, cardiovascular diseases (CVD) remain the leading cause of mortality throughout the world. The prevalence of the main risk factors (RF) for CVD varies ethnically and geographically. Single observations witness that native and non­native populations inhabiting various, often quite contrast climatic and geographical, as socialeconomic conditions, might show a broad variety in CVD and RF prevalence.Aim. To evaluate the 4­year survival rate in association with the RF and cardiovascular morbidity and mortality among rural inhabitants of Russia and Kyrgyz Republic, with analysis of ethnic specifics (by the data from trial “Interepid”).Material and methods. The study was conducted under the framework of international project “Interepid” that included momentary epidemiological study of the prevalence of the main chronic non­communicable diseases and RF, and prospective step in small town and rural settlements of two countries — Russia and Kyrgyz Republic. In the analysis the results included of representative selections of rural inhabitants of the Volzhskiy region of Samarskaya Oblast of Russia (n=1050), and of Chuyskaya Oblast of Kyrgyz Republic (n=1341), age 20­64 y. o. In Russia and in Kyrgyz Republic the study was done by one protocol Interepid with specifically developed surveys (2011­2012). To the analysis, the endpoints included: all­cause mortality, CVD mortality, non­fatal cardiovascular events: non­fatal myocardial infarction, non­fatal stroke or transient ischemia, unstable angina, revascularization of any vascular pool — coronary bypass, endovascular revascularization, carotid endarterectomy, lower limbs arteries revascularization.Results. The standardised by age survival rate was higher among the Kyrgyz Republic inhabitants — 98,8%, and in Samarskaya oblast — 95,7%. In Kyrgyz Republic the fatal and non­fatal cardiovascular endpoints were registered in 14,7% responders, with no ethnical differences, and in Samarskaya oblast — only in 2,1% (p
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