Age-dependent changes of coagulation system parameters in pediatric patients of cardiosurgical profile

Autor:	N. B. Karakhalis, A. Kh. Kade, A. V. Bratova
Jazyk:	ruština
Rok vydání:	2020
Předmět:	coagulation childhood age developing hemostasis reference values Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Diseases of the circulatory (Cardiovascular) system RC666-701 Surgery RD1-811 Medical emergencies. Critical care. Intensive care. First aid RC86-88.9
Zdroj:	Инновационная медицина Кубани, Vol 0, Iss 1, Pp 23-29 (2020)
Druh dokumentu:	article
ISSN:	2541-9897 2500-0268
DOI:	10.35401/2500-0268-2020-17-1-23-29
Popis:	Objective. Estimate baseline coagulation profile values in patients scheduled for cardiosurgical intervention in age groups of pediatric population.Material and Methods. The coagulation profile was analyzed in a complete selection of patients admitted to the intensive care department of Scientific Research Institute – Ochapovsky Regional Clinical Hospital no. 1 for the period from January to December 2018. The study includes 842 patients planned for cardiac surgery.Results. This study demonstrates the dependence of the basic parameters of the hemostasis system on age characteristics, mainly during the period of the first year of life. APPT values were similar in all age groups, whereas extended PV was recorded in patients less than one year.Conclusion. Evaluation of coagulation system parameters should be based on age-specific reference values. Understanding the concept of developing hemostasis is extremely important in conditions of optimal prevention, diagnosis and treatment of hemorrhagic and thrombotic conditions in the pediatric population.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/8cc610f593914dc0bd157a1f8861539d Zobrazit plný text záznamu View record in DOAJ