| Popis: |
In this study, we evaluate the effects of Weizmannia coagulans SANK70258 intake on skin condition and defecation, both alone and in combination with galacto-oligosaccharides, by conducting a randomized, double-blind, parallel-group, placebo-controlled, eight-week study of 45 healthy individuals. The primary endpoints were measurement of the stratum corneum moisture content, transepidermal water loss, and skin texture; the secondary endpoints were skin assessment, a defecation survey, and measurement of fecal organic acid and p-cresol contents. The participants were divided into a W. coagulans SANK70258 alone (lac + dex) group, a W. coagulans SANK70258 plus galacto-oligosaccharides (lac + gal) group, and a placebo (dex) group. The lac + gal group showed a decrease in skin roughness and fecal p-cresol content. Scaliness was improved in lac + dex and lac + gal groups. Thus, synbiotics combining W. coagulans SANK70258 and galacto-oligosaccharides can improve scaliness and skin roughness and reduce fecal p-cresol content. |
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