Oral and uterine leiomyomas exhibit high immunoexpression of Cripto-1 compared to normal myometrium

Autor: ANDRÉ F. SILVA, EMMILY C.C. DA SILVA, CLÁUDIA N. OLIVEIRA, KEYLA B.F. ROCHA, MARCIA C.C. MIGUEL, JOABE S. PEREIRA
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Anais da Academia Brasileira de Ciências, Vol 92, Iss 4 (2020)
Druh dokumentu: article
ISSN: 1678-2690
0001-3765
DOI: 10.1590/0001-3765202020200519
Popis: Abstract Leiomyomas are the most common benign tumors in women. Many of them are associated with significant morbidity. The present study aimed to analyze histomorphological and histochemical characteristics and immunoexpression of Cripto-1 in oral leiomyomas (OL), uterine leiomyomas (UL), and normal myometrium (NM). Sample was composed of ten OL, 11 UL and 11 NM. Histomorphological characteristics were analyzed at 100 and 400x magnifications with HE staining. The immunoexpression of Cripto-1 was analyzed in five high-power fields. Statistical analysis considered a significant difference when p
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