Reasons for Crown Failures in Primary Teeth: Protocol for a Systematic Review and Meta-Analysis

Autor: Stephan Lampl, Deepa Gurunathan, Jogikalmat Krithikadatta, Deepak Mehta, Desigar Moodley
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: JMIR Research Protocols, Vol 12, p e51505 (2023)
Druh dokumentu: article
ISSN: 1929-0748
DOI: 10.2196/51505
Popis: BackgroundThere is a tendency nowadays to restore large defects in primary dentition with pediatric crowns instead of conventional restorations. Thus, understanding the factors contributing to the survival or failure of dental crowns in pediatric dentistry is essential for optimizing treatment outcomes. ObjectiveThe primary objective of this protocol is to outline the methodological approach for analyzing data from observational studies and randomized controlled trials to investigate reasons for the failure of dental crowns in primary teeth and to compute their survival and failure rates. MethodsA comprehensive literature review will be performed in electronic databases, including PubMed (MEDLINE), Cochrane, Embase, and Web of Science. As per predefined inclusion criteria, we will include observational studies (prospective clinical studies) and randomized clinical trials that have an English abstract and involve children aged 1-10 years undergoing crown restorations. Two independent reviewers will independently screen all retrieved records and full-text articles and extract data. The study’s methodological quality will be appraised using suitable tools. Assessments of publication bias will be performed using funnel plots. The findings will be described qualitatively for the systematic review. If possible, a meta-analysis will be performed to estimate failure rates by dividing the number of failures by the total exposure time. A Poisson regression model, assuming constant event rates, will be used to compute 3-year and 5-year survival proportions. The Pearson goodness-of-fit statistics will be used to assess the heterogeneity of the model. A P value
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