Lipid Peroxidation in the Plasma, Lungs, Heart and Liver of Broilers Fed a Grape Seed Extract and Raised at 2278 m of Altitude

Autor: LT Rodríguez-Ortega, G Juárez-Juárez, A Pro-Martínez, E Sosa-Montes, J Bautista-Ortega, F González-Cerón, AJ Vargas-Galicia, D Chan-Díaz, D Moreno-Medina, J Gallegos-Sánchez, A Rodríguez-Ortega
Jazyk: angličtina
Předmět:
Zdroj: Brazilian Journal of Poultry Science, Vol 19, Iss 3, Pp 465-470
Druh dokumentu: article
ISSN: 1806-9061
DOI: 10.1590/1806-9061-2016-0408
Popis: ABSTRACT The aim of this research was to evaluate the effect of partial substitution of vitamin E (VE) by grape seed extract (GSE) on glutathione peroxidase activity (GPxA), nitric oxide (NO) concentration and lipid peroxidation [malondialdehyde (MDA) concentration] in the plasma, lungs, heart and liver, and live performance of broilers raised at 2278 m of altitude. One-d-old Ross 308 male chickens (n = 420) were randomly distributed into three treatments: Control-AL (basal diet containing 40 IU of VE and fed ad libitum; AL), Control-FR (basal diet and feed restriction; FR) and GSE-AL [basal diet containing 10 mg of GSE (equivalent to 30 IU VE) plus 10 IU of VE and fed AL]. The data were analyzed using one-way analysis of variance. Glutathione peroxidase activity, and NO and MDA concentrations in the plasma were evaluated on d 46. On d 47, MDA was evaluated in the lungs, heart and liver. Live performance parameters were recorded weekly. There were no significant differences (p>0.05) in live performance and NO concentration among treatments. Birds from the GSE-AL treatment presented the lowest (p
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