Neutrophil-to-lymphocyte ratio predicts functionally significant coronary artery stenosis in patients with stable coronary artery disease

Autor: Samet Yılmaz, Uğur Canpolat, Kazim Başer, Sefa Ünal, Mevlüt Serdar Kuyumcu, Sinan Aydoğdu
Jazyk: English<br />Turkish
Rok vydání: 2018
Předmět:
Zdroj: Türk Kardiyoloji Derneği Arşivi, Vol 46, Iss 2, Pp 129-135 (2018)
Druh dokumentu: article
ISSN: 1016-5169
DOI: 10.5543/tkda.2017.16709
Popis: Objective: The aim of this study was to determine the relationship between the neutrophil-to-lymphocyte ratio (NLR) and the functional severity of coronary stenosis assessed according to the fractional flow reserve (FFR) in stable coronary artery disease (CAD). Methods: The clinical and laboratory data of 420 patients who underwent index coronary angiography for stable angina pectoris were analyzed retrospectively. The functional severity of an intermediate lesion was determined by FFR. An FFR value of >0.80 was considered non-significant (Group 1), whereas ≤0.80 was accepted as significant stenosis (Group 2). Results: A total of 137 (32.6%) patients had functionally significant coronary artery stenosis. The median NLR value was significantly greater in Group 2 compared with Group 1 [3.13 (0.93–9.75) vs 2.22 (0.75–6.02); p
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