Plasticity in visual cortex is disrupted in a mouse model of tauopathy

Autor: Amalia Papanikolaou, Fabio R. Rodrigues, Joanna Holeniewska, Keith G. Phillips, Aman B. Saleem, Samuel G. Solomon
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Druh dokumentu: article
ISSN: 2399-3642
DOI: 10.1038/s42003-022-03012-9
Popis: Amalia Papanikolaou and Fabio Rodrigues et al. examine visual cortical function and intrinsic plasticity using the rTg4510 tauopathy mouse model. They demonstrate that, while basal visual cortical responses seem largely unaffected, intrinsic plasticity and the behavioural response to a visual stimulus is compromised, even in young rTg4510 mice.
Databáze: Directory of Open Access Journals