Portal vein thrombosis in patients with COVID-19: A systematic review

Autor: Hany Abdelfatah El-hady, El-Sayed Mahmoud Abd-Elwahab, Gomaa Mostafa-Hedeab, Mohamed Shawky Elfarargy
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Asian Journal of Surgery, Vol 46, Iss 8, Pp 3017-3026 (2023)
Druh dokumentu: article
ISSN: 1015-9584
DOI: 10.1016/j.asjsur.2022.11.002
Popis: Several studies have proven that COVID-19 is linked to a higher incidence of different thrombotic events. Thrombosis of the portal vein can result in portal hypertension and can extend to the mesenteric vein resulting in intestinal ischemia. A search of PubMed, Web of Science, and Scopus for relevant studies revealed an association between PVT and COVID-19. This review is structured according to PRISMA guidelines. Thirty-three studies met the inclusion criteria. Twenty-nine case studies/series and four cohort/cross-sectional studies were included. Age at diagnosis was lower when compared to PVT due to cirrhosis. In cohort/cross-sectional studies, males comprised 54.83% of subjects, whereas in case reports/series, males comprised 62.1%. Obesity, asthma, hypertension, and diabetes were the most common comorbidities identified. The majority of the thrombotic events occurred within two weeks. The treatment aimed to prevent thrombus progression and improve recanalization. According to the evidence, early intervention prevents the poor prognosis of intestinal ischemia and its propagation.
Databáze: Directory of Open Access Journals