Association between RDW-SD and prognosis across glycemic status in patients with dilated cardiomyopathy

Autor: Jian Zhang, Xinqing Li, Yuhui Zhang, Jiayu Feng, Yani Huang, Liyan Huang, Xuemei Zhao, Anran Xin, Chengyi Wang
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: BMJ Open Diabetes Research & Care, Vol 12, Iss 6 (2024)
Druh dokumentu: article
ISSN: 2052-4897
DOI: 10.1136/bmjdrc-2024-004478
Popis: Introduction The prognostic significance of red cell distribution width-SD (RDW-SD) as a promising inflammatory biomarker in individuals with non-ischemic dilated cardiomyopathy (DCM) and varying glycemic status remains unexplored.Research design and methods Patients hospitalized for DCM in Fuwai Hospital from 2006 to 2021 were retrospectively included. The primary outcome encompassed all-cause mortality and heart transplantations. The multivariable Cox regression was used to evaluate the association between RDW-SD and outcomes in the overall DCM population, and among patients with normoglycemia (NG), pre-diabetes mellitus (pre-DM) and DM.Results Among 1,102 patients with DCM, the median age was 48 years and 23.5% were women. In the overall DCM cohort, the RDW-SD was independently associated with the primary outcome (adjusted HR 1.29, 95% CI 1.15 to 1.45, p
Databáze: Directory of Open Access Journals