Engineering rules that minimize germline silencing of transgenes in simple extrachromosomal arrays in C. elegans

Autor: Mohammed D. Aljohani, Sonia El Mouridi, Monika Priyadarshini, Amhed M. Vargas-Velazquez, Christian Frøkjær-Jensen
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-020-19898-0
Popis: C. elegans has strong repressive mechanisms that silence transgenes in the germline. Here the authors elucidate the design rules for efficient germline expression.
Databáze: Directory of Open Access Journals