Comparison of disinfective power according to application order of 70% isopropyl alcohol and 10% povidone-iodine
| Autor: | Sang Su Kim, Soo-Bong Yu, Joo-Duck Kim, Sie Jeong Ryu |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | Korean Journal of Anesthesiology, Vol 65, Iss 6, Pp 519-524 (2013) |
| Druh dokumentu: | article |
| ISSN: | 2005-6419 2005-7563 20797486 |
| DOI: | 10.4097/kjae.2013.65.6.519 |
| Popis: | BackgroundMany disinfectants have been used clinically in both single and combination applications, but there have been few studies on disinfective power according to sterilization sequence when using a combination of disinfectants. The purpose of this study was to evaluate the disinfective power of a combination of 70% isopropyl alcohol and 10% povidone-iodine (PVP-I) according to sterilization sequence.MethodsTwo hundred healthy volunteers were recruited. Subjects were disinfected with a combination of 70% isopropyl alcohol and 10% PVP-I on both forearms, in varying sequence. The AP group included disinfections on the left forearm with isopropyl alcohol first followed by 10% PVP-I, while the PA group included disinfections on the right forearm with same disinfectants in reverse order. Skin cultures were obtained using cotton swabs 3 min after application of each disinfectant, and then were inoculated on blood agar plates for bacterial culture. Cultures were incubated at 37℃ under aerobic conditions for 48 hours.ResultsThere was no significant difference in the number of positive cultures after the 1st disinfection (AP, 45; PA, 36, P = 0.262) or the 2nd disinfection (AP, 6; PA, 13, P = 0.157), suggesting that there is no relationship between disinfective power and the sequence of the disinfectants used. The number of positive cultures significantly decreased after the 2nd disinfection (P < 0.01), however.ConclusionsThere was no significant difference in disinfective power according to sterilization sequence with 70% isopropyl alcohol and 10% PVP-I in healthy volunteers. The combination of 70% isopropyl alcohol and 10% PVP-I was more effective than disinfection with a single agent regardless of sterilization sequence. |
| Databáze: | Directory of Open Access Journals |
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