| Autor: |
Ryan J. Slaby, C. Nikki Arrington, Jeffrey Malins, Rose A. Sevcik, Kenneth R. Pugh, Robin Morris |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Journal of Neurodevelopmental Disorders, Vol 15, Iss 1, Pp 1-15 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1866-1955 |
| DOI: |
10.1186/s11689-023-09495-9 |
| Popis: |
Abstract Background Developmental dyslexia (DD) and attention deficit/hyperactivity disorder (ADHD) are highly comorbid neurodevelopmental disorders. Individuals with DD or ADHD have both been shown to have deficits in white matter tracts associated with reading and attentional control networks. However, white matter diffusivity in individuals comorbid with both DD and ADHD (DD + ADHD) has not been specifically explored. Methods Participants were 3rd and 4th graders (age range = 7 to 11 years; SD = 0.69) from three diagnostic groups ((DD (n = 40), DD + ADHD (n = 22), and typical developing (TD) (n = 20)). Behavioral measures of reading and attention alongside measures of white matter diffusivity were collected for all participants. Results DD + ADHD and TD groups differed in mean fractional anisotropy (FA) for the left and right Superior Longitudinal Fasciculus (SLF)-Parietal Terminations and SLF-Temporal Terminations. Mean FA for the DD group across these SLF tracts fell between the lower DD + ADHD and higher TD averages. No differences in mean diffusivity nor significant brain-behavior relations were found. Conclusions Findings suggest that WM diffusivity in the SLF increases along a continuum across DD + ADHD, DD, and TD. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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