Intervention of roasted cashew nut supplement against endothelial renal vasoconstriction disease in hypertensive rats exposed to mixed-fractionated petroleum products

Autor: J.K. Akintunde, A.O. Okunubi, O.A. Dosumu, A.T. Omidiran, A.D. Folayan, S.O. Salami
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Clinical Nutrition Open Science, Vol 58, Iss , Pp 183-205 (2024)
Druh dokumentu: article
ISSN: 2667-2685
DOI: 10.1016/j.nutos.2024.10.005
Popis: Summary: There have been increasing concerns about the great risks posed by petroleum products which contribute to the progression endothelial renal vasoconstriction and hypertension. This study aims to investigate the modulatory effects of Roasted cashew nut on rats induced with endothelial renal vasoconstriction syndrome upon exposure to mixed fractionated petroleum products (MFPP). Seventy male albino rats were randomized into seven (n=10) groups. Group I (normal control) was given distilled water. Group II was administered with MFPP (20 %/day). Group III was administered with MFPP (20 %/day) + atenolol (50 mg/kg). Group IV was administered with MFPP (20 %/day) + 10 % roasted cashew nut (10 %RCN). Group V was administered with MFPP (20 %/day) + (20 %RCN). Group VI was treated with 10 %RCN while Group VII was treated with 20 %RCN. Data were analyzed using one-way analysis of variance (ANOVA) and Duncan's multiple range test with P
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