| Autor: |
Minseok Yoon, Duhyeon Kim, Seonghui Kim, Min Young Um, Yung Hyun Choi, Suengmok Cho |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Journal of Functional Foods, Vol 115, Iss , Pp 106117- (2024) |
| Druh dokumentu: |
article |
| ISSN: |
1756-4646 |
| DOI: |
10.1016/j.jff.2024.106117 |
| Popis: |
The aim of this study was to investigate the effects of chronic administration (21 days) of phlorotannin supplement (PS) on sleep and compare them with the effects of diazepam (DZP), a benzodiazepine hypnotic drug. DZP significantly decreased sleep latency and increased non-rapid eye movement sleep amount on day 1 of administration compared with those at baseline; however, its effects diminished over the administration period. On the contrary, PS showed significant sleep-promoting effects throughout the study period, with no significant difference in efficacy between days 1 and 21. Notably, PS did not cause any changes in the slow wave activity (SWA) throughout the treatment period; whereas, DZP decreased the SWA on day 1 of administration. These results suggest that chronic administration of PS does not induce tolerance, implying its consistent sleep-maintaining effects. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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Full Text from ScienceDirect