Organic anion transporter 1 is an HDAC4-regulated mediator of nociceptive hypersensitivity in mice
| Autor: | Christian Litke, Anna M. Hagenston, Ann-Kristin Kenkel, Eszter Paldy, Jianning Lu, Rohini Kuner, Daniela Mauceri |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022) |
| Druh dokumentu: | article |
| ISSN: | 2041-1723 34234829 |
| DOI: | 10.1038/s41467-022-28357-x |
| Popis: | Chronic pain is sustained by alterations in gene transcription. Here, the authors show that increased expression of Organic Anionic Transporter 1 in the spinal cord is epigenetically controlled and key to hypersensitivity in pathological pain. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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