Transformation of Two Cases of Lung Adenocarcinoma into Pulmonary Sarcomatoid Carcinoma following Treatment

Autor:	Zhenyu Yang, Yinfang Shen, Junhong Jiang, Ziyi Liu, Chuanyong Mu
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	Diseases of the respiratory system RC705-779
Zdroj:	Canadian Respiratory Journal, Vol 2021 (2021)
Druh dokumentu:	article
ISSN:	1198-2241 1916-7245
DOI:	10.1155/2021/6661772
Popis:	Accumulating evidence shows that histologic transformation is involved in the drug resistance of lung cancer. Moreover, it is common for lung adenocarcinoma to transform into small-cell lung cancer or squamous cell carcinoma; however, clinical cases with sarcomatoid transformation have been rarely reported. Thus, both the diagnosis and treatment of lung adenocarcinoma with sarcomatoid transformation remain difficult. Here, we discuss two patients with lung adenocarcinoma with sarcomatoid transformation—analyzing the diagnosis, clinical features, immunohistochemical characteristics, therapy, and prognosis—with the hope that this report will be used as a reference for future treatment of these patients.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/8bf37488d07e4355b3403bc4166c53d0 Zobrazit plný text záznamu Plný text View record in DOAJ