| Autor: |
Ivana Ságová, Daniela Kantárová, Marián Mokáň, Peter Vaňuga |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
International Journal of Endocrinology, Vol 2022 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
1687-8345 |
| DOI: |
10.1155/2022/8766046 |
| Popis: |
Objective. Median neuropathy is a common manifestation of acromegaly, although its pathology is uncertain. Changes in levels of growth hormone (GH) and insulin-like growth factor I (IGF-I) and body composition are potential parameters in pathology of median neuropathy in acromegaly. We aimed to assess changes in the cross-sectional area (CSA) of the median nerve and body composition in newly diagnosed acromegalic patients 1 year after treatment and to determine their mutual relationships. Design. This prospective study included 30 patients with newly diagnosed acromegaly and 30 healthy controls matched for age, gender, and body mass index. Physical and laboratory examinations, dual-energy X-ray absorptiometry (DXA), and ultrasound evaluations were performed at baseline and 1 year after initial treatment. Results. The CSA of the median nerve was increased in acromegalic patients compared with controls (13.1 mm2 [12.2–14.9] vs 7.5 mm2 [6.4–8.4], P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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