Ocular allergy and keratoconus
| Autor: | Namrata Sharma, Kavita Rao, Prafulla K Maharana, Rasik B Vajpayee |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Epidemiology
keratoconus prevalence Disease pathogenesis genetic heterogeneity genetics and genomics genome-wide association study genomic loci linkage mapping molecular mechanisms whole exome-genome sequencing Deregulation ectasia gene expression mass spectroscopy proteomics signaling pathways Cornea crosslinking modulus Corneal topography imaging optical coherence tomography placido disc based topography Ectatic disease scheimpflug imaging Keratoconus ocular allergy vernal keratoconjunctivitis Ophthalmology RE1-994 |
| Zdroj: | Indian Journal of Ophthalmology, Vol 61, Iss 8, Pp 407-409 (2013) |
| Druh dokumentu: | article |
| ISSN: | 0301-4738 1998-3689 |
| DOI: | 10.4103/0301-4738.116063 |
| Popis: | Keratoconus is the most common corneal ectatic disorder, the cause of which is largely unknown. Many factors have been implicated, and the ocular allergy is being one of them. The commonly proposed pathogenesis includes the release of inflammatory mediators due to eye rubbing which may alter the corneal collagen and lead to corneal ectasias. The onset of keratoconus is often early in cases associated with allergy and routine corneal topography may detect subtle forms of keratoconus. These cases may require early keratoplasty and are at an increased risk of having acute corneal hydrops. Surgical outcomes are similar to primary keratoconus cases. However, post-operative epithelial breakdown may be a problem in these cases. Control of allergy and eye rubbing is the best measure to prevent corneal ectasias in cases of ocular allergy. |
| Databáze: | Directory of Open Access Journals |
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