Capsule Switching among C:2b:P1.2,5 Meningococcal Epidemic Strains after Mass Immunization Campaign, Spain

Autor: Belén Alcalá, Luisa Arreaza, Celia Salcedo, María J. Uría, Laura De La Fuente, Julio A. Vázquez
Jazyk: angličtina
Rok vydání: 2002
Předmět:
Zdroj: Emerging Infectious Diseases, Vol 8, Iss 12, Pp 1512-1514 (2002)
Druh dokumentu: article
ISSN: 1080-6040
1080-6059
DOI: 10.3201/eid0812.020081
Popis: A mass immunization campaign for 18-month to 19-year-olds was undertaken in Spain in 1996–1997 because of an epidemic of serogroup C meningococcal disease associated with a C:2b:P1.2,5 strain belonging to the A4 lineage. Surveillance for the “capsule-switching” phenomenon producing B:2b:P1.2,5 isolates was undertaken. Of 2,975 meningococci characterized, B:2b:P1.2,5 and B:2b:P1.2 antigenic combinations were found in 18 isolates; 15 meningococci were defined as serogroup B belonging to the A4 lineage.
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