Systemic Treatment of Vitreous Inflammation

Autor: John B. Christoforidis, Susie Chang, Angela Jiang, Jillian Wang, Colleen M. Cebulla
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Mediators of Inflammation, Vol 2012 (2012)
Druh dokumentu: article
ISSN: 0962-9351
1466-1861
DOI: 10.1155/2012/936721
Popis: Non infectious vitreous inflammation is often vision threatening and can be associated with potentially life-threatening systemic conditions. Treatment is often challenging as it involves systemic medications that can be associated with adverse effects. The classes of drugs are ever expanding and include corticosteroids, antimetabolites, alkylating agents, T-cell and calcineurin agents, biologic agents, and interferons. Each class of systemic therapy for non-infectious vitreous inflammation is reviewed. We discuss the mechanisms of action, usual clinical dosages, the specific conditions that are treated, the adverse effects, and usual course of treatment for each class of therapy.
Databáze: Directory of Open Access Journals