Advances in AIDS Chemotherapy: The Asymmetric Synthesis of CRIXIVAN®

Autor: Paul J. Reider
Jazyk: German<br />English<br />French
Rok vydání: 1997
Předmět:
Zdroj: CHIMIA, Vol 51, Iss 6 (1997)
Druh dokumentu: article
ISSN: 0009-4293
2673-2424
Popis: The discovery and development of an efficient, practical asymmetric synthesis of the HIV Protease inhibitor CRIXIVAN® is described. Particular emphasis is placed on the selective installation of each of the five stereogenic centers as well as design strategies associated with the preparation of a complex pharmaceutical agent needed in multiton quantities.
Databáze: Directory of Open Access Journals