Advances in AIDS Chemotherapy: The Asymmetric Synthesis of CRIXIVAN®
Autor: | Paul J. Reider |
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Jazyk: | German<br />English<br />French |
Rok vydání: | 1997 |
Předmět: | |
Zdroj: | CHIMIA, Vol 51, Iss 6 (1997) |
Druh dokumentu: | article |
ISSN: | 0009-4293 2673-2424 |
Popis: | The discovery and development of an efficient, practical asymmetric synthesis of the HIV Protease inhibitor CRIXIVAN® is described. Particular emphasis is placed on the selective installation of each of the five stereogenic centers as well as design strategies associated with the preparation of a complex pharmaceutical agent needed in multiton quantities. |
Databáze: | Directory of Open Access Journals |
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