Autor: |
Yuki Ota, Yoko Obata, Takahiro Takazono, Masato Tashiro, Tomotaro Wakamura, Akinori Takahashi, Yui Shiozawa, Taiga Miyazaki, Tomoya Nishino, Koichi Izumikawa |
Jazyk: |
angličtina |
Rok vydání: |
2021 |
Předmět: |
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Zdroj: |
BMC Nephrology, Vol 22, Iss 1, Pp 1-12 (2021) |
Druh dokumentu: |
article |
ISSN: |
1471-2369 |
DOI: |
10.1186/s12882-021-02450-7 |
Popis: |
Abstract Background Hypokalemia and acute kidney injury (AKI) occur in patients administered liposomal amphotericin B (L-AMB), a wide-spectrum anti-fungicidal drug. However, the association between potassium supplementation and the occurrence of AKI in patients with hypokalemia who were administered L-AMB is not well understood. Methods Using nationwide claims data and laboratory data, the occurrence of AKI during L-AMB treatment was retrospectively compared between patients with hypokalemia who were or were not supplemented with potassium and between those adequately or inadequately supplemented with potassium (serum potassium levels corrected to ≥3.5 mEq/L or remained |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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