Desmoplastic small round cell tumor of the ovary: A rare but poor prognostic disease in a young woman!

Autor:	Ravi Hari Phulware, Maitrayee Roy, Neeta Singh, Sunesh Kumar, Sandeep R Mathur
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	desmoplastic small round cell tumor dsrct ovarian tumor small round blue cell tumor young women Pathology RB1-214 Microbiology QR1-502
Zdroj:	Indian Journal of Pathology and Microbiology, Vol 64, Iss 1, Pp 206-209 (2021)
Druh dokumentu:	article
ISSN:	0377-4929
DOI:	10.4103/IJPM.IJPM_725_19
Popis:	Desmoplastic small round cell tumor (DSRCT) is a rare, aggressive neoplasm of uncertain histogenesis that preferentially involves the abdominal and pelvic cavities. DSRCT mainly develops in adolescent and young adults with a strong male predominance; the male to female ratio is 4:1. Ovarian location is exceptional. DSRCT generally develops in the abdomen and have a tendency towards peritoneal spread, with subsequent metastasis to distant lymph nodes, liver and lungs. It is a poorly understood malignancy with a very characteristic morphology, immunophenotype, cytogenetic features, and poor prognosis. This tumor can co-express epithelial, neuronal, and mesenchymal markers. Despite intensive therapy, including surgery, radiotherapy and chemotherapy, and immunotherapy; the 5-year survival is less than 15%.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/8b68a87da076470e83771f3a916903cd Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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