Unusual presentation of medullary thyroid carcinoma: Regional and distant metastases in the background of benign non-neoplastic Multi-Nodular Goiter

Autor: Samiah S. Al-Angari, Mohammed AlEssa, Tariq Al-Johani
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Otolaryngology Case Reports, Vol 6, Iss C, Pp 31-33 (2018)
Druh dokumentu: article
ISSN: 2468-5488
DOI: 10.1016/j.xocr.2017.12.003
Popis: Background: Medullary Thyroid Carcinoma (MTC) is a malignancy that primarily arises from the C-cells of the thyroid gland with a tendency to regional and distant metastases. Methods: We report a case of a 34-year-old female with MTC where there was no evidence of primary foci of the disease within the thyroid gland, while there was a widespread metastasis in the cervical lymph nodes, lungs, abdomen, and vertebrae. Results: The patient was diagnosed with metastatic sporadic MTC based on the pre-operative work up. She underwent completion thyroidectomy with bilateral neck dissection levels II-VI. The post-operative histopathology report confirmed the diagnosis. Conclusion: The case report shows an unusual presentation of MTC. It demonstrates that there is an entity of metastatic sporadic MTC, confirmed by an abnormal calcitonin level, with unknown primary.
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