Evaluation of anterior mediastinal solid tumors by CT perfusion: a preliminary study
| Autor: | Selim Bakan, Sedat Giray Kandemirli, Atilla Süleyman Dikici, Ezel Erşen, Onur Yıldırım, Cesur Samancı, Şebnem Batur, Deniz Çebi Olgun, Fatih Kantarcı, Canan Akman |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Diagnostic and Interventional Radiology, Vol 23, Iss 1, Pp 10-14 (2017) |
| Druh dokumentu: | article |
| ISSN: | 1305-3825 1305-3612 |
| DOI: | 10.5152/dir.2016.16093 |
| Popis: | PURPOSE:We aimed to assess the role of computed tomography (CT) perfusion in differentiation of thymoma from thymic hyperplasia, lymphoma, thymic carcinoma, and lung cancer invading anterior mediastinum.METHODS:In this study, 25 patients with an anterior mediastinal lesion underwent CT perfusion imaging from January 2015 to February 2016. Diagnoses included thymoma (n=7), thymic hyperplasia (n=8), lymphoma (n=4), thymic carcinoma (n=3), and invasive lung cancer (n=3). Lymphoma, thymic carcinoma, and lung cancer were grouped as malignant tumors for statistical analysis. Values for blood flow, blood volume, and permeability surface were measured in CT perfusion.RESULTS:Blood flow and blood volume values were higher in thymoma in comparison to thymic hyperplasia; however, the difference was not statistically significant. Blood volume values were significantly higher in thymoma (mean, 11.4 mL/100 mL; range, 5.2–20.2 mL/100 mL) compared with lymphoma (mean, 5.3 mL/100 mL; range, 2.5–7.2 mL/100 mL) (P = 0.023). Blood flow and blood volume values were significantly higher in thymoma compared with non-thymoma malignant tumors (P = 0.025).CONCLUSION:CT perfusion is helpful in differentiating thymoma from non-thymoma malignancies including lymphoma, thymic carcinoma, and invasive lung cancer involving the anterior mediastinum. |
| Databáze: | Directory of Open Access Journals |
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