Development of custom lead shield and strainer for targeted irradiation for mice in the gamma cell chamber

Autor: Nurhaslina Hasan, Nur Fatihah Ronny Sham, Muhammad Khalis Abdul Karim, Syed Baharom Syed Ahmad Fuad, Narimah Abdul Hamid Hasani, Effat Omar, Mohammad Johari Ibahim
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-021-93964-5
Popis: Abstract We presented a development of a custom lead shield and mouse strainer for targeted irradiation from the gamma-cell chamber. This study was divided into two parts i.e., to (i) fabricate the shield and strainer from a lead (Pb) and (ii) optimize the irradiation to the mice-bearing tumour model with 2 and 8 Gy absorbed doses. The lead shielding was fabricated into a cuboid shape with a canal on the top and a hole on the vertical side for the beam path. Respective deliveries doses of 28 and 75 Gy from gamma-cell were used to achieve 2 and 8 Gy absorbed doses at the tumour sites.
Databáze: Directory of Open Access Journals
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