Construction and validation of coronary heart disease risk prediction model for general hospitals in Tacheng Prefecture, Xinjiang, China

Autor: Yikang Xu, Jingru Ma, Yang Yang, Limin Liu, Xinran Zhao, Yu Wang, Alimu Mijiti, Qiangru Cheng, Jun Ma
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Frontiers in Cardiovascular Medicine, Vol 11 (2024)
Druh dokumentu: article
ISSN: 2297-055X
DOI: 10.3389/fcvm.2024.1514103
Popis: ObjectiveTo analyze the risk factors for coronary heart disease (CHD) in patients hospitalized in general hospitals in the Tacheng Prefecture, Xinjiang, and to construct and verify the nomogram prediction model for the risk of CHD.MethodsFrom June 2022 to June 2023, 489 CHD patients (CHD group) and 520 non-CHD individuals (control group) in Tacheng, Xinjiang, were retrospectively selected. Using a 7:3 ratio, patients were divided into a training group (706 cases) and a validation group (303 cases). General clinical data were compared, and key variables were screened using logistic regression (AIC). A CHD risk nomogram for Tacheng was constructed. Model performance was assessed using ROC AUC, calibration curves, and DCA.ResultsIn the training group, non-Han Chinese (OR = 2.93, 95% CI: 2.0–4.3), male (OR = 1.65, 95% CI: 1.0–2.7), alcohol consumption (OR = 1.82, 95% CI: 1.2–2.9), hyperlipidemia (OR = 2.41, 95% CI: 1.7–3.5), smoking (OR = 1.61, 95% CI: 1.0–2.6), diabetes mellitus (OR = 1.62, 95% CI: 1.1–2.4), stroke (OR = 2.39, 95% CI: 1.6–3.7), older age (OR = 1.08, 95% CI: 1.1–1.2), and larger waist circumference (OR = 1.04, 95% CI: 1.0–1.1) were the risk factors for coronary heart disease (all P
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