Milky spots reactions to schistosomal mansoni infection

Autor: H. L. Lenzi, D. N. Oliveira, R. Borojevic, J. A. Lenzi
Jazyk: angličtina
Rok vydání: 1992
Předmět:
Zdroj: Memorias do Instituto Oswaldo Cruz, Vol 87, Pp 111-116 (1992)
Druh dokumentu: article
ISSN: 0074-0276
1678-8060
DOI: 10.1590/S0074-02761992000900017
Popis: Milky spots (MS), considered by the authors as a Coelomatic Lympho-myelopoietic Organ (CLMO), present a strong reactivity during experimental schistosomal mansoni infection, characterized by an increase of lymphocytes, macrophages, plasmocytes, mast cells, neutrophils and expression of eosinophil metaplasia. Intraperitoneal injection of purified Schistosoma mansoni (Sm) eggs provoked a rise in the number and size of MS, which developed the sessile marginal and pedunculated types. The authors conclude that egg antigens are, at least partially, responsible for MS reactivity during Sm infection.
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