Autor: |
Diane N. Sayah, OD, PhD, Denise Descovich, MD, Santiago Costantino, PhD, Mark R. Lesk, MD, MSc |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
Ophthalmology Science, Vol 4, Iss 6, Pp 100576- (2024) |
Druh dokumentu: |
article |
ISSN: |
2666-9145 |
DOI: |
10.1016/j.xops.2024.100576 |
Popis: |
Purpose: To assess the relationship between the pulsatile choroidal volume change (ΔV) and ocular rigidity (OR), an important biomechanical property of the eye. Design: This is a prospective cross-sectional study. Subjects: Two hundred seventeen participants (235 eyes) were included in this study. Of those, 18 eyes (18 participants) had exudative retinal disease, and 217 eyes (199 participants) had open-angle glaucoma (39.2%), suspect discs (12.4%), ocular hypertension (14.3%), or healthy eyes (34.1%). Methods: Pulsatile choroidal volume change was measured using dynamic OCT, which detects the change in choroidal thickness during the cardiac cycle. Ocular rigidity was measured using an invasive procedure as well as using a validated optical method. Correlations between ΔV and OR were assessed in subjects with healthy eyes, eyes with glaucoma, or eyes with exudative retinal disease. Main Outcome Measures: Ocular rigidity and pulsatile ocular volume change. Results: In 18 eyes where OR was obtained invasively and ΔV was obtained noninvasively, a significant correlation was found between ΔV and OR (rs = −0.664, P = 0.003). Similarly, a strong inverse correlation was found between the noninvasive measurements of both ΔV and OR (rs = −0.748, P |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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