Understanding heparin-induced thrombosis: A brief review

Autor: Mariela Irabien-Zúñiga, Edgar A. Rojas-Guerrero, David Gómez-Almaguer
Jazyk: English<br />Spanish; Castilian
Rok vydání: 2021
Předmět:
Zdroj: Medicina Universitaria, Vol 23, Iss 3 (2021)
Druh dokumentu: article
ISSN: 21000026
1665-5796
2530-0709
DOI: 10.24875/RMU.21000026
Popis: Heparin has been the first line for treatment and prevention of thrombosis for a while. However, one of its non-hemorrhagic effects remains noticeable: heparin-induced thrombocytopenia, mediated by antibodies directed to complexes of platelet factor, and heparin. Binding to platelet FcγRIIA receptors initiates platelet aggregation and its thrombotic effect. Incidence of heparin-induced thrombocytopenia (HIT) ranges from
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