Understanding heparin-induced thrombosis: A brief review
Autor: | Mariela Irabien-Zúñiga, Edgar A. Rojas-Guerrero, David Gómez-Almaguer |
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Jazyk: | English<br />Spanish; Castilian |
Rok vydání: | 2021 |
Předmět: | |
Zdroj: | Medicina Universitaria, Vol 23, Iss 3 (2021) |
Druh dokumentu: | article |
ISSN: | 21000026 1665-5796 2530-0709 |
DOI: | 10.24875/RMU.21000026 |
Popis: | Heparin has been the first line for treatment and prevention of thrombosis for a while. However, one of its non-hemorrhagic effects remains noticeable: heparin-induced thrombocytopenia, mediated by antibodies directed to complexes of platelet factor, and heparin. Binding to platelet FcγRIIA receptors initiates platelet aggregation and its thrombotic effect. Incidence of heparin-induced thrombocytopenia (HIT) ranges from |
Databáze: | Directory of Open Access Journals |
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