Association of Cannabis Use Disorder With Hospitalizations for Pulmonary Embolism and Subsequent in‐Hospital Mortality in Young Adults: A Contemporary Nationwide Analysis

Autor: Rupak Desai, Nitin Ghadge, Sai Gautham Kanagala, Nishanth Katukuri, Alpha James, Avinash Kadiyala, Sai Diksha Vutukuru, Meghana Kotharu, Tajdin Borzoo, Akhila Nalla, Ankit Vyas, Shivani Priyadarshni, Mostafa Shalaby, Wissam Khalife
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 13 (2024)
Druh dokumentu: article
ISSN: 2047-9980
DOI: 10.1161/JAHA.123.032787
Popis: Background With the increase in popularity of cannabis and its use and the lack of large‐scale data on cannabis use and venous thromboembolism and pulmonary embolism (PE), we used a nationally representative cohort of young adults (aged 18–44 years) to compare the odds of admissions and in‐hospital mortality of PE with and without cannabis use disorder (CUD). Methods and Results Identified patients with PE using the National Inpatient Sample (2018) were compared for baseline, comorbidities, and outcomes. Multivariable regression analysis, adjusted for covariates, was used to compare the odds of PE in young patients with CUD (CUD+) versus those without (CUD−) and those with prior venous thromboembolism. Propensity score–matched analysis (1:6) was also performed to assess in‐hospital outcomes. A total of 61 965 (0.7%) of 8 438 858 young adult admissions in 2018 were PE related, of which 1705 (0.6%) had CUD+. On both unadjusted (odds ratio, 0.80 [95% CI, 0.71–0.90]; P
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