Chromatin remodeller Fun30Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation

Autor: Junwoo Lee, Eun Shik Choi, Hogyu David Seo, Keunsoo Kang, Joshua M. Gilmore, Laurence Florens, Michael P. Washburn, Joonho Choe, Jerry L. Workman, Daeyoup Lee
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/ncomms14527
Popis: Nucleosomes have been shown to impede the elongation of RNA polymerase II during transcription. Here, the authors provide evidence that in fission yeast chromatin remodeller Fun30Fft3 localizes to transcribing regions to promote transcription by nucleosome disassembly in vivo.
Databáze: Directory of Open Access Journals