Comparison of mechanical dermabrasion and CO2 laser in cultured epithelial sheets transplantation in the treatment of refractory stable vitiligo: A multicenter, prospective and self‐controlled comparative study

Autor: Luyan Tang, Zhuyu Luo, Jian Li, Qi Zhang, Shujun Chen, Jinran Lin, Weimin Shi, Xingyu Mei, Yichen Tang, Yuchong Chen, Jinfeng Wu, Wenyu Wu, Jinhua Xu
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: JEADV Clinical Practice, Vol 2, Iss 4, Pp 901-907 (2023)
Druh dokumentu: article
ISSN: 2768-6566
DOI: 10.1002/jvc2.241
Popis: Abstract Background Vitiligo is an acquired depigmented disorder that causes great damage to patient's appearance and mental health. Surgical treatment plays a vital role in patients with refractory vitiligo. Recipient‐site preparation (such as liquid nitrogen, mechanical dermabrasion, chemical peeling and laser) is a key step in surgical treatment. Among them, mechanical dermabrasion and CO2 laser can achieve accurate ablation in different parts and depths. Objectives To compare the advantages and disadvantages of mechanical dermabrasion and CO2 laser and their preference for different parts in cultured epithelial sheets transplantation for the treatment of vitiligo. Methods We used a self‐controlled study to compare the efficacy of mechanical dermabrasion and CO2 laser in 120 stable vitiligo patients of different parts at different time points after cultured epithelial sheets transplantation. Results No overall difference between the mechanical dermabrasion group and the CO2 laser group. While the recovery rate of different parts of the mechanical dermabrasion group was significantly different (p
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