Effect of Intrathecal Baclofen Pump on Scoliosis in Children With Cerebral Palsy: A Meta-Analysis

Autor: Soolim Lee, Cheolhwan Hyun, Kyungmin KIM, Hyo Eun Kwon, Minwoo Woo, Seong-Eun Koh
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Annals of Rehabilitation Medicine, Vol 47, Iss 1, Pp 11-18 (2023)
Druh dokumentu: article
ISSN: 2234-0645
2234-0653
DOI: 10.5535/arm.22108
Popis: Objective To systematically review the effect of intrathecal baclofen pump insertion in children with cerebral palsy (CP) with respect to scoliosis. Methods A systematic literature search was conducted in PubMed, Embase, Cochrane Library, and Google Scholar databases up to June 2022. The inclusion criteria were as follows: (1) studies with a quantitative study design; (2) studies with a study group of children with CP; (3) studies comparing scoliosis in children with and without an intrathecal baclofen pump; and (4) studies with Cobb’s angle as a parameter. Results Of the 183 studies found, four studies, all of which were retrospective comparative studies, met the aforementioned inclusion criteria. All studies were homogeneous (I2=0%, p=0.53) and intrathecal baclofen pump insertion accelerated the progression of scoliosis (standard mean difference=0.27; 95% confidence interval=0.07–0.48). Conclusion Intrathecal baclofen pumps have been used to alleviate spasticity in children with CP, thus aiding their daily activities and movements. However, their advantages and disadvantages should be reviewed after sufficient time considering the pumps’ negative effect on the course of scoliosis.
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