Cloning and expression of ricin a- and b-subunits genes in fusion constructions with dihydrofolate reductase gene in escheriсhia coli.
Autor: | M. А. Gracheva, Z. М. Galushkina, N. N. Poletaeva, L. V. Verhovskaya, V. G. Lunin, V. I. Shvets |
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Jazyk: | ruština |
Rok vydání: | 2007 |
Předmět: | |
Zdroj: | Тонкие химические технологии, Vol 2, Iss 6, Pp 40-47 (2007) |
Druh dokumentu: | article |
ISSN: | 2410-6593 2686-7575 |
Popis: | Recombinant chimeric constructions RTA-DHFR and RTВ-DHFR consisting of ricin Aand B-subunits genes (RTA and RTB) and dihydrofolate reductase (DHFR) gene were cloned and expressed in Escheriсhia coli. Antigenic properties of RTA and RTB retained in chimeric proteins RTA-DHFR and RTВ-DHFR. |
Databáze: | Directory of Open Access Journals |
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