Cloning and expression of ricin a- and b-subunits genes in fusion constructions with dihydrofolate reductase gene in escheriсhia coli.

Autor: M. А. Gracheva, Z. М. Galushkina, N. N. Poletaeva, L. V. Verhovskaya, V. G. Lunin, V. I. Shvets
Jazyk: ruština
Rok vydání: 2007
Předmět:
Zdroj: Тонкие химические технологии, Vol 2, Iss 6, Pp 40-47 (2007)
Druh dokumentu: article
ISSN: 2410-6593
2686-7575
Popis: Recombinant chimeric constructions RTA-DHFR and RTВ-DHFR consisting of ricin Aand B-subunits genes (RTA and RTB) and dihydrofolate reductase (DHFR) gene were cloned and expressed in Escheriсhia coli. Antigenic properties of RTA and RTB retained in chimeric proteins RTA-DHFR and RTВ-DHFR.
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