Copper intrauterine device increases vaginal concentrations of inflammatory anaerobes and depletes lactobacilli compared to hormonal options in a randomized trial

Autor: Bryan P. Brown, Colin Feng, Ramla F. Tanko, Shameem Z. Jaumdally, Rubina Bunjun, Smritee Dabee, Anna-Ursula Happel, Melanie Gasper, Donald D. Nyangahu, Maricianah Onono, Gonasagrie Nair, Thesla Palanee-Phillips, Caitlin W. Scoville, Kate Heller, Jared M. Baeten, Steven E. Bosinger, Adam Burgener, Jo-Ann S. Passmore, Renee Heffron, Heather B. Jaspan
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-023-36002-4
Popis: Here, in a randomized trial, the authors comparatively evaluate the effect of a copper intrauterine device versus other contraceptive options on the vaginal environment after one and six consecutive months of use, finding to exert changes on the vaginal microbiota that may potentially lead to detrimental sex and reproductive health.
Databáze: Directory of Open Access Journals