In Vitro Synergy of Levofloxacin Plus Piperacillin/Tazobactam against Pseudomonas aeruginosa

Autor: Vladimir Chachanidze, Aixa Curbelo-Irizarry, Deborah Ashcraft, George Pankey
Jazyk: angličtina
Rok vydání: 2009
Předmět:
Zdroj: Interdisciplinary Perspectives on Infectious Diseases, Vol 2009 (2009)
Druh dokumentu: article
ISSN: 1687-708X
1687-7098
DOI: 10.1155/2009/984934
Popis: In vitro synergy testing using levofloxacin (LVX) plus piperacillin/tazobactam (TZP) was performed by Etest and time-kill assay (TKA) for 31 unique fluoroquinolone-resistant Pseudomonas aeruginosa isolates. The Etest method showed synergy for 9/31 (29%) of isolates, while TKA showed synergy with 14/31 (45%) of isolates. When comparing the Etest method and TKA, concordant results for synergy, antagonism, and indifference were obtained for 24/31 (77%) of the isolates tested.
Databáze: Directory of Open Access Journals