In Vitro Synergy of Levofloxacin Plus Piperacillin/Tazobactam against Pseudomonas aeruginosa
Autor: | Vladimir Chachanidze, Aixa Curbelo-Irizarry, Deborah Ashcraft, George Pankey |
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Jazyk: | angličtina |
Rok vydání: | 2009 |
Předmět: | |
Zdroj: | Interdisciplinary Perspectives on Infectious Diseases, Vol 2009 (2009) |
Druh dokumentu: | article |
ISSN: | 1687-708X 1687-7098 |
DOI: | 10.1155/2009/984934 |
Popis: | In vitro synergy testing using levofloxacin (LVX) plus piperacillin/tazobactam (TZP) was performed by Etest and time-kill assay (TKA) for 31 unique fluoroquinolone-resistant Pseudomonas aeruginosa isolates. The Etest method showed synergy for 9/31 (29%) of isolates, while TKA showed synergy with 14/31 (45%) of isolates. When comparing the Etest method and TKA, concordant results for synergy, antagonism, and indifference were obtained for 24/31 (77%) of the isolates tested. |
Databáze: | Directory of Open Access Journals |
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