Comparison of urinary adiponectin in the presence of metabolic syndrome in peri- and postmenopausal women

Autor: Patsama Vichinsartvichai, Rattana Teeramara, Titima Jirasawas, Prirayapak Sakoonwatanyoo
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: BMC Women's Health, Vol 22, Iss 1, Pp 1-7 (2022)
Druh dokumentu: article
ISSN: 1472-6874
DOI: 10.1186/s12905-022-01655-8
Popis: Abstract Objectives To find the association between urinary adiponectin and metabolic syndrome (MetS) in peri- and postmenopausal women and its potential application as a noninvasive screening for MetS. Methods A cross-sectional study was conducted in healthy peri- and postmenopausal women (defined by STRAW + 10 staging) aged at least 40 years who attended annual check-ups or menopause clinics were recruited. Baseline demographic data, MENQOL, anthropometric measurements, blood pressure, laboratory (FBS, total cholesterol, HDL-C, LDL-C, TG), and urinary adiponectin were collected. The MetS was diagnosed according to JIS 2009. Results 290 peri- and postmenopausal women had participated. The prevalence of Mets among our participants was 18%. Urinary adiponectin levels were similar in peri- and postmenopausal women with and without MetS (2.6 ± 2.2 vs. 2.3 ± 1.9 ng/mL, respectively, P = 0.55). Urinary adiponectin provides no diagnostic value for MetS (AUC = 0.516). Conclusions Urinary adiponectin has no role in screening and diagnosing MetS in peri- and postmenopausal women. The quest toward noninvasive screening for MetS is still going on.
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