Evaluation of Antifungal Effectiveness of a Novel Probiotic Toothpaste: An In-vitro Study
| Autor: | Pavita Kataria, Harpreet Singh |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Journal of Clinical and Diagnostic Research, Vol 16, Iss 8, Pp ZC22-ZC26 (2022) |
| Druh dokumentu: | article |
| ISSN: | 2249-782X 0973-709X |
| DOI: | 10.7860/JCDR/2022/55875.16752 |
| Popis: | Introduction: There is increasing public interest in probiotic healthcare products since their discovery by Élie Metchnikoff in the early 20th century. This trend is not only visible in supermarkets and dental practices, but also in the scientific world. An increasing number of clinical trials and laboratory investigations are being conducted to validate the claims made about these products with regards to their antifungal properties. Aim: To evaluate the antifungal properties of commercially available probiotic, anticaries toothpaste, Purexa, against Candida albicans in-vitro. Materials and Methods: An in-vitro study was carried out for a period of three months from December 2021 to February 2022 in the Department of Microbiology, Baba Jaswant Singh Dental College and Research Institute, Patiala, Punjab, India. Two wells were prepared in each blood agar plate containing lawn cultures of Candida albicans. The plates were incubated at 37˚C for 24 hours. Purexa toothpaste was poured into one well as test material. The second well was filled with distilled water to act as control. A total of 10 sample plates were made. Antifungal activity was assessed by measuring the Zone of Inhibition (ZOI) in millimeters (mm) using a digital vernier caliper after 24, 48 and 72 hours, and then after one week. Increasing width of zones of inhibition indicated definite antifungal activity of Purexa toothpaste. A p-value |
| Databáze: | Directory of Open Access Journals |
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