SARS-CoV2 mutations and impact on mortality: observational study in a sub-saharan Africa hospital

Autor: Jean-Robert Makulo, Roger Wumba, Madone Ndona Mandina, Placide Mbala, Adrienne Amuri Aziza, Yannick Mayamba Nlandu, Benjanmin Kabwe, Donatien Mangala, Ben Izizag Bepouka, Jerome Ossam Odio, Murielle Longokolo, Eric Mukenge, Guyguy Kamwiziku, Eddy Lusamaki Kingand, Constantin Bashengezi, Gilbert Kabanda, Benjamin Longo-Mbenza
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Virology Journal, Vol 20, Iss 1, Pp 1-6 (2023)
Druh dokumentu: article
ISSN: 1743-422X
DOI: 10.1186/s12985-023-02014-1
Popis: Summary Background One year after the coronavirus disease 2019 (COVID-19) pandemic, the focus of attention has shifted to the emergence and spread of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants of concern (VOCs). The aim of the study was to assess the frequency of VOCs in patients followed for COVID-19 at Kinshasa university hospital (KUH) during the 3rd and 4th waves of the pandemic in Kinshasa. Hospital mortality was compared to that of the first two waves. Method The present study included all patients in whom the diagnosis of SARS-CoV-2 infection was confirmed by the polymerase chain reaction (PCR). The laboratory team sequenced a subset of all SARS-CoV-2 positive samples with high viral loads define as Ct
Databáze: Directory of Open Access Journals
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