| Autor: |
Bart R. Maas, Bastiaan R. Bloem, Yoav Ben-Shlomo, Luc J.W. Evers, Rick C. Helmich, Johanna G. Kalf, Marjolein A. van der Marck, Marjan J. Meinders, Alice Nieuwboer, Maarten J. Nijkrake, Jorik Nonnekes, Bart Post, Ingrid H.W.M. Sturkenboom, Marcel M. Verbeek, Nienke M. de Vries, Bart van de Warrenburg, Tessa van de Zande, Marten Munneke, Sirwan K.L. Darweesh |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Clinical Parkinsonism & Related Disorders, Vol 8, Iss , Pp 100185- (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2590-1125 |
| DOI: |
10.1016/j.prdoa.2023.100185 |
| Popis: |
Background: Females, people with young-onset PD and older individuals, and non-white populations are historically underrepresented in clinical Parkinson’s disease (PD) research. Furthermore, research traditionally focused predominantly on motor symptoms of PD. Including a representative and diverse group of people with PD and also studying non-motor symptoms is warranted to better understand heterogeneity in PD and to generalize research findings. Objective: This project aimed to determine whether, within a consecutive series of PD studies performed within a single center in the Netherlands: (1) the proportion of included females, mean age and proportion of native Dutch people changed over time; and 2) reports of the ethnicity of participants and the proportion of studies with non-motor outcomes changed over time. Methods: Characteristics of participants and non-motor outcomes were analyzed using a unique dataset of summary statistics of studies with a large number of participants conducted at a single center during a 19-year period (2003–2021). Results: Results indicate no relationship between calendar time and proportion of females (mean 39 %), mean age (66 years), proportion of studies that reported ethnicity, and proportion of native Dutch people in studies (range 97–100 %). The proportion of participants in whom non-motor symptoms were assessed increased, but this difference was consistent with chance. Conclusion: Study participants in this center reflect the PD population in the Netherlands in terms of sex, but older individuals and non-native Dutch individuals are under-represented. We have still a lot to do in ensuring adequate representation and diversity in PD patients within our research. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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