| Autor: |
Ilke Sen, Xin Zhou, Alexey Chernobrovkin, Nataly Puerta-Cavanzo, Takaharu Kanno, Jérôme Salignon, Andrea Stoehr, Xin-Xuan Lin, Bora Baskaner, Simone Brandenburg, Camilla Björkegren, Roman A. Zubarev, Christian G. Riedel |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-019-13931-7 |
| Popis: |
The transcription factor DAF-16/FOXO mediates a wide variety of aging-preventive responses by driving the expression of stress resistance and longevity promoting genes. Here the authors show that transcriptional initiation at many DAF-16/FOXO target genes requires the dephosphorylation of SPT-5 by Protein Phosphatase 4. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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