Correlation between nutritional assessment and oxidative stress in candidates for liver transplant

Autor: Ana Carolina Cavalcante Viana, Fernanda Maria Machado Maia, Natália Sales de Carvalho, Suelyne Rodrigues de Morais, Alane Nogueira Bezerra, Priscila da Silva Mendonça, Sâmia Lopes da Costa, Ana Filomena Camacho Santos Daltro
Jazyk: English<br />Portuguese
Rok vydání: 2019
Předmět:
Zdroj: Einstein (São Paulo), Vol 18 (2019)
Druh dokumentu: article
ISSN: 2317-6385
DOI: 10.31744/einstein_journal/2020ao4039
Popis: ABSTRACT Objective To evaluate the oxidative profile, nutritional status and food intake (caloric value; macronutrients; vitamins A, E and C; and zinc), and to correlate oxidative stress with nutritional status in patients who were candidates for liver transplant. Methods This is a cross-sectional, analytical, and descriptive study with 51 candidates for liver transplant. Sociodemographic and clinical data, anthropometric parameters, food consumption, and a 10mL blood sample were collected from each patient. Oxidative stress was analyzed by the thiobarbituric acid method. The consumption of macronutrients, caloric value and micronutrients (zinc, vitamins A, E and C) were qualitatively analyzed, and zinc was also quantitatively analyzed. Results The mean age was 49.17±8.17 years. The highest percentage of malnutrition was according to arm muscle circumference (56.86%), followed by arm circumference (52.94%), triceps skin fold (50.98%), and body mass index (1.96%). The mean malondialdehyde level was 14.80±8.72μM/L, presenting a negative correlation with the body mass index for patients with liver cirrhosis according to IMC-Campillo values (p=0.001; r=-0.430). Low energy, carbohydrate, protein, vitamin A and E consumption were observed in more than 50% of subjects. Conclusion This study showed an association of nutritional status through body mass index for patients with liver cirrhosis according to IMC-Campillo, with oxidative stress in patients with liver cirrhosis on a liver transplant waiting list.
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