Rapid progression of disease in two cases of undifferentiated endometrial carcinoma

Autor: Krista S. Pfaendler, Leslie M. Randall
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Gynecologic Oncology Reports, Vol 27, Iss , Pp 65-68 (2019)
Druh dokumentu: article
ISSN: 2352-5789
DOI: 10.1016/j.gore.2019.01.004
Popis: Undifferentiated endometrial carcinoma, a rare histopathologic diagnosis, has a poor prognosis with high risk of progression during or shortly after completion of adjuvant treatment. We present two cases of undifferentiated endometrial carcinoma: one in a postmenopausal female who experienced recurrent disease immediately after completion of adjuvant treatment and one in a premenopausal female who experienced disease progression while receiving adjuvant treatment. These cases exemplify the aggressive behavior of undifferentiated endometrial carcinoma and suggest the need for a more effective treatment in the upfront setting than the current standard of care for endometrioid endometrial adenocarcinoma. Keywords: Undifferentiated endometrial carcinoma, Endometrial cancer, Dedifferentiated endometrial carcinoma
Databáze: Directory of Open Access Journals